Younghoon Kim Selected Research

N- (4- methyl- 3- (1- methyl- 7- (6- methylpyridin- 3- ylamino)- 2- oxo- 1,2- dihydropyrimido(4,5- d)pyrimidin- 3(4H)- yl)phenyl)- 3- (trifluoromethyl)benzamide

4/2021	Novel and Potent Small Molecules against Melanoma Harboring BRAF Class I/II/III Mutants for Overcoming Drug Resistance.
1/2021	Novel Small Molecules Capable of Blocking mtRAS-Signaling Pathway.

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Younghoon Kim Research Topics

Disease

27	Neoplasms (Cancer) 04/2024 - 03/2009
9	Stomach Neoplasms (Stomach Cancer) 01/2022 - 10/2015
8	Inflammation (Inflammations) 04/2024 - 05/2009
5	Infections 01/2021 - 01/2014
4	Colitis 11/2023 - 07/2021
3	Bacterial Infections (Bacterial Infection) 01/2024 - 01/2011
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 04/2020
3	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2020 - 05/2012
3	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 08/2014
3	Neoplasm Metastasis (Metastasis) 11/2017 - 08/2014
3	Ischemia 08/2013 - 01/2010
2	Adenocarcinoma 04/2024 - 10/2023
2	Pancreatic Neoplasms (Pancreatic Cancer) 04/2024 - 05/2023
2	Body Weight (Weight, Body) 01/2024 - 01/2015
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2023 - 01/2023
2	Edema (Dropsy) 01/2023 - 10/2019
2	Carcinogenesis 01/2019 - 01/2016
2	Microsatellite Instability 01/2019 - 08/2014
2	Retinoblastoma (Glioblastoma, Retinal) 09/2017 - 02/2017
2	Breast Neoplasms (Breast Cancer) 04/2010 - 12/2009
1	Muscular Atrophy (Muscle Atrophy) 04/2024
1	Atrophy 04/2024
1	Sarcopenia 04/2024
1	Diabetes Mellitus 01/2024
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2024
1	Obesity 01/2024
1	Carcinoma (Carcinomatosis) 04/2023
1	Bites and Stings (Sting) 01/2023
1	Diarrhea 07/2022
1	Metaplasia 01/2022

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2024 - 03/2009
5	Anti-Bacterial Agents (Antibiotics)IBA 01/2024 - 01/2011
4	Biomarkers (Surrogate Marker)IBA 04/2024 - 12/2009
3	AcidsIBA 11/2023 - 09/2012
3	EnzymesIBA 05/2023 - 08/2013
3	Dextran SulfateIBA 01/2023 - 07/2021
3	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 08/2014
3	Messenger RNA (mRNA)IBA 12/2021 - 08/2013
3	MucinsIBA 01/2020 - 12/2014
2	AlbuminsIBA 04/2024 - 04/2020
2	Adenosine Triphosphate (ATP)IBA 01/2024 - 08/2013
2	LigandsIBA 05/2023 - 05/2018
2	InterferonsIBA 01/2023 - 05/2015
2	Calcibiotic Root Canal SealerIBA 03/2022 - 08/2014
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2022
2	AntigensIBA 12/2021 - 01/2017
2	Membrane Proteins (Integral Membrane Proteins)IBA 12/2021 - 01/2021
2	Apolipoproteins E (ApoE)IBA 08/2021 - 01/2021
2	N- (4- methyl- 3- (1- methyl- 7- (6- methylpyridin- 3- ylamino)- 2- oxo- 1,2- dihydropyrimido(4,5- d)pyrimidin- 3(4H)- yl)phenyl)- 3- (trifluoromethyl)benzamideIBA 04/2021 - 01/2021
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 04/2021 - 01/2021
2	micaIBA 01/2021 - 01/2020
2	AntibodiesIBA 01/2021 - 01/2020
2	ParaffinIBA 01/2019 - 01/2016
2	Formaldehyde (Formol)FDA Link 01/2019 - 01/2016
2	CholesterolIBA 01/2018 - 05/2012
2	human ERBB2 proteinIBA 01/2018 - 10/2015
2	Transcription Factors (Transcription Factor)IBA 11/2017 - 10/2015
2	hydrogen sulfite (bisulfite)IBA 08/2017 - 01/2017
2	JNK Mitogen-Activated Protein KinasesIBA 11/2016 - 06/2016
2	Sirtuin 1IBA 02/2016 - 01/2016
2	honokiolIBA 05/2015 - 01/2015
2	magnololIBA 05/2015 - 01/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2015 - 05/2013
2	Glucose (Dextrose)FDA LinkGeneric 08/2013 - 08/2013
2	CalciumIBA 08/2013 - 09/2008
2	Sodium AzideIBA 08/2013 - 08/2013
1	Interleukin-6 (Interleukin 6)IBA 04/2024
1	Indicators and Reagents (Reagents)IBA 04/2024
1	Branched-Chain Amino AcidsIBA 04/2024
1	Dexamethasone (Maxidex)FDA LinkGeneric 04/2024
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2024
1	LipidsIBA 01/2024
1	Dopamine (Intropin)FDA LinkGeneric 01/2024
1	Carboxylic AcidsIBA 01/2024
1	Pyruvic Acid (Pyruvate)IBA 01/2024
1	Metformin (Glucophage)FDA LinkGeneric 01/2024
1	MicroRNAs (MicroRNA)IBA 11/2023
1	ImmunosorbentsIBA 05/2023
1	sinapinic acidIBA 01/2023
1	Sucrose (Saccharose)IBA 01/2023
1	SolutionsIBA 01/2023
1	Tight Junction ProteinsIBA 01/2023
1	N(1)-methyl-2-lysergic acid diethylamide (MIL)IBA 11/2022
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2022
1	AmmoniaIBA 07/2022
1	AminesIBA 07/2022
1	PhenolsIBA 07/2022
1	Protein MethyltransferasesIBA 01/2022
1	Apolipoproteins B (ApoB)IBA 01/2022
1	Phenobarbital (Luminal)FDA Link 01/2022
1	AntralIBA 01/2022
1	MethyltransferasesIBA 01/2022
1	Neuraminidase (Sialidase)IBA 12/2021
1	Lipid NanoparticlesIBA 12/2021

Therapy/Procedure

3	Adjuvant Chemotherapy 04/2023 - 01/2015
3	Therapeutics 01/2022 - 03/2009
1	Kidney Transplantation 01/2024
1	Phage Therapy 01/2024
1	Gastrectomy 10/2023
1	Fecal Microbiota Transplantation 01/2023